Carbossiemoglobina: composto che si forma all’interno del globulo rosso per unione della parte proteica dell’emoglobina con il monossido di carbonio (CO), quando questo gas si trova nell’aria respirata a una pressione parziale sufficiente per occupare sull’emoglobina il sito normalmente legato dall’ossigeno. Rispetto all’ossigeno il monossido di carbon has an affinity for hemoglobin 200-300 times higher. The carboxyhemoglobin is difficult to dissociate and is responsible for a severe form of hypoxia, anemic hypoxia that, which can cause polycythemia.
carboxyhemoglobin concentrations higher than 20% involve mild symptoms of intoxication, over 50% involve intoxication and coma can be fatal. Therefore, death occurs from asphyxia. The effect of CO is higher in altitude, the reduced percentage of oxygen in the air. In case of poisoning should immediately take the affected person to fresh air, for breathing oxygen enriched air helps eliminate of CO from carboxyhemoglobin. A concentration of CO in the air equal to 2000-4000 ppm (0.2% -0.4%) is fatal in about 15 minutes, after having caused loss of consciousness. In the presence of 1000 ppm survived about 90 minutes.
are The first symptoms of headache and feel dizzy, unfortunately, the gas also causes drowsiness, and this often prevents victims to warn of the danger and ventilate the room.
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